This presentation will take a look at proven, thorough, yet sensible approaches to ensuring that your business is in the best position to create solid user requirements for your informatics system (e.g. LIMS, ELN, LES, CDS). Overcoming different obstacles such as lack of resources, inconsistent work processes, lack of informatics “experts”, and lack of business motivation within the company will also be addressed. In addition to generating a solid, well thought out user requirements document, the presentation will provide ways to also leverage the requirements generation exercise to improve communication, morale, and work processes, all while having a little bit of fun.